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Metabolic Consequences of Neuronal HIF1α-Deficiency in Mediobasal Hypothalamus in Mice

OBJECTIVE: This study aims to investigate whether hypoxia-inducible factor 1α (HIF1α) in the neurons of the mediobasal hypothalamus is involved in the regulation of body weight, glucose, and lipid metabolism in mice and to explore the underlying molecular mechanisms. METHODS: HIF1α (flox/flox) mice...

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Detalles Bibliográficos
Autores principales: Rozjan, Azmat, Shan, Weibi, Yao, Qiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558296/
https://www.ncbi.nlm.nih.gov/pubmed/34733235
http://dx.doi.org/10.3389/fendo.2021.668193