An antibody against Siglec-15 promotes bone formation and fracture healing by increasing TRAP(+) mononuclear cells and PDGF-BB secretion

Osteoporosis (OP) is a common age-related disease characterized by a deterioration of bone mass and structure that predisposes patients to fragility fractures. Pharmaceutical therapies that promote anabolic bone formation in OP patients and OP-induced fracture are needed. We investigated whether a n...

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Detalles Bibliográficos
Autores principales: Zhen, Gehua, Dan, Yang, Wang, Ruomei, Dou, Ce, Guo, Qiaoyue, Zarr, Melissa, Liu, Linda N., Chen, Lieping, Deng, Ruoxian, Li, Yusheng, Shao, Zengwu, Cao, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558327/
https://www.ncbi.nlm.nih.gov/pubmed/34719673
http://dx.doi.org/10.1038/s41413-021-00161-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558327/
https://www.ncbi.nlm.nih.gov/pubmed/34719673
http://dx.doi.org/10.1038/s41413-021-00161-1

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