Sharp-Wave Ripple Frequency and Interictal Epileptic Discharges Increase in Tandem During Thermal Induction of Seizures in a Mouse Model of Genetic Epilepsy

Dravet Syndrome (DS) is a genetic, infantile-onset epilepsy with refractory seizures and severe cognitive impairment. While network level pathophysiology is poorly understood, work in genetic mouse models of DS reveals selective reduction of inhibitory interneuron excitability, a likely mechanism of...

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Detalles Bibliográficos
Autores principales: Cheah, Christine S., Beckman, Megan A., Catterall, William A., Oakley, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558377/
https://www.ncbi.nlm.nih.gov/pubmed/34733140
http://dx.doi.org/10.3389/fncel.2021.751762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558377/
https://www.ncbi.nlm.nih.gov/pubmed/34733140
http://dx.doi.org/10.3389/fncel.2021.751762

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