Comprehensive Analysis of LIN28A in Chinese Patients With Early Onset Parkinson’s Disease

A loss-of-function variant in Lin-28 Homolog A gene (LIN28A p. R192G, rs558060339) has been identified in two East Asian ancestry patients with early-onset PD (EOPD). Functional studies revealed that such a variant could lead to developmental defects and PD-related phenotype, and the phenotypes coul...

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Detalles Bibliográficos
Autores principales: Gu, Xiaojing, Hou, Yanbing, Chen, Yongping, Ou, Ruwei, Cao, Bei, Wei, Qianqian, Zhang, Lingyu, Song, Wei, Zhao, Bi, Wu, Ying, Shang, Huifang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558378/
https://www.ncbi.nlm.nih.gov/pubmed/34733315
http://dx.doi.org/10.3389/fgene.2021.740096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558378/
https://www.ncbi.nlm.nih.gov/pubmed/34733315
http://dx.doi.org/10.3389/fgene.2021.740096

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