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Identification and Validation of a Malignant Cell Subset Marker-Based Polygenic Risk Score in Stomach Adenocarcinoma Through Integrated Analysis of Bulk and Single-Cell RNA Sequencing Data

Objectives: The aim of the present study was to construct a polygenic risk score (PRS) for poor survival among patients with stomach adenocarcinoma (STAD) based on expression of malignant cell markers. Methods: Integrated analyses of bulk and single-cell RNA sequencing (scRNA-seq) of STAD and normal...

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Detalles Bibliográficos
Autores principales: Zou, Qiyuan, Lv, Yufeng, Gan, Zuhuan, Liao, Shulan, Liang, Zhonghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558465/
https://www.ncbi.nlm.nih.gov/pubmed/34733840
http://dx.doi.org/10.3389/fcell.2021.720649