PADI4 Polymorphisms Confer Risk of Anti-CCP-Positive Rheumatoid Arthritis in Synergy With HLA-DRB1*04 and Smoking

Peptidylarginine deiminases (PADs) catalyze citrullination, a post-translational modification playing a pathogenic role in anti-citrullinated protein antibody (ACPA)-positive rheumatoid arthritis (RA). The interplay between single nucleotide polymorphisms (SNPs) in the PADI genes and known risk fact...

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Detalles Bibliográficos
Autores principales: Massarenti, Laura, Enevold, Christian, Damgaard, Dres, Ødum, Niels, Garred, Peter, Frisch, Morten, Shelef, Miriam A., Jacobsen, Søren, Nielsen, Claus Henrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558474/
https://www.ncbi.nlm.nih.gov/pubmed/34733271
http://dx.doi.org/10.3389/fimmu.2021.707690

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558474/
https://www.ncbi.nlm.nih.gov/pubmed/34733271
http://dx.doi.org/10.3389/fimmu.2021.707690

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