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Peripheral Inflammation Results in Increased Excitability of Capsaicin-Insensitive Nociceptive DRG Neurons Mediated by Upregulation of ASICs and Voltage-Gated Ion Channels

Previously, we have characterized the capsaicin-insensitive low pH-sensitive (caps(−)lpH(+)) subtype of small-sized nociceptive dorsal root ganglion (DRG) neurons that express acid-sensing ion channels, T-type Ca(2+) channels, and have isolectin B4-negative phenotype. These neurons demonstrated incr...

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Detalles Bibliográficos
Autores principales: Duzhyy, Dmytro E., Voitenko, Nana V., Belan, Pavel V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558483/
https://www.ncbi.nlm.nih.gov/pubmed/34733139
http://dx.doi.org/10.3389/fncel.2021.723295