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Mesenchymal Stem Cells With Cancer-Associated Fibroblast-Like Phenotype Stimulate SDF-1/CXCR4 Axis to Enhance the Growth and Invasion of B-Cell Acute Lymphoblastic Leukemia Cells Through Cell-to-Cell Communication

Background: Bone marrow mesenchymal stem cells (BM-MSCs) are the stromal cells in the leukemia microenvironment, and can obtain cancer-associated fibroblast (CAF)-like phenotype under certain conditions to further promote leukemia progression. However, the mechanism of MSCs with CAF-like phenotype i...

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Detalles Bibliográficos
Autores principales: Pan, Chengyun, Fang, Qin, Liu, Ping, Ma, Dan, Cao, Shuyun, Zhang, Luxin, Chen, Qingzhen, Hu, Tianzhen, Wang, Jishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558501/
https://www.ncbi.nlm.nih.gov/pubmed/34733839
http://dx.doi.org/10.3389/fcell.2021.708513