APC-Targeted DNA Vaccination Against Reticulocyte-Binding Protein Homolog 5 Induces Plasmodium falciparum-Specific Neutralizing Antibodies and T Cell Responses

Targeted delivery of antigen to antigen presenting cells (APCs) is an efficient way to induce robust antigen-specific immune responses. Here, we present a novel DNA vaccine that targets the Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5), a leading blood-stage antigen of the hum...

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Detalles Bibliográficos
Autores principales: Bjerkan, Louise, Visweswaran, Ganesh Ram R., Gudjonsson, Arnar, Labbé, Geneviève M., Quinkert, Doris, Pattinson, David J., Spång, Heidi C. L., Draper, Simon J., Bogen, Bjarne, Braathen, Ranveig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558525/
https://www.ncbi.nlm.nih.gov/pubmed/34733274
http://dx.doi.org/10.3389/fimmu.2021.720550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558525/
https://www.ncbi.nlm.nih.gov/pubmed/34733274
http://dx.doi.org/10.3389/fimmu.2021.720550

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