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Decreased IgG Antibody Response to Viral Protein Mimotopes of Oncogenic Merkel Cell Polyomavirus in Sera From Healthy Elderly Subjects

Merkel cell polyomavirus (MCPyV) is the main causative agent of Merkel cell carcinoma (MCC), a rare but aggressive skin tumor with a typical presentation age >60 years. MCPyV is ubiquitous in humans. After an early-age primary infection, MCPyV establishes a clinically asymptomatic lifelong infect...

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Detalles Bibliográficos
Autores principales: Mazziotta, Chiara, Lanzillotti, Carmen, Govoni, Marcello, Pellielo, Giulia, Mazzoni, Elisa, Tognon, Mauro, Martini, Fernanda, Rotondo, John Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558529/
https://www.ncbi.nlm.nih.gov/pubmed/34733278
http://dx.doi.org/10.3389/fimmu.2021.738486