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Anatase and Rutile TiO(2) Nanoparticles Lead Effective Bone Damage in Young Rat Model via the IGF-1 Signaling Pathway

PURPOSE: To evaluate the effects of anatase and rutile TiO(2) nanoparticles (NPs) on the growth and development of bones in young rats and explore their possible mechanisms. METHODS: Three-week-old male rats were orally administered anatase TiO(2) NPs and rutile TiO(2) NPs for 28 days. The indicator...

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Detalles Bibliográficos
Autores principales: Cheng, Wenshu, Xu, Xinyue, Lang, Yuanyuan, Cheng, Zugen, Rizwan, Mohammad, Tang, Xiaomin, Xie, Lixin, Liu, Yanling, Xu, Hengyi, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558833/
https://www.ncbi.nlm.nih.gov/pubmed/34737562
http://dx.doi.org/10.2147/IJN.S333632