HVEM structures and mutants reveal distinct functions of binding to LIGHT and BTLA/CD160

HVEM is a TNF (tumor necrosis factor) receptor contributing to a broad range of immune functions involving diverse cell types. It interacts with a TNF ligand, LIGHT, and immunoglobulin (Ig) superfamily members BTLA and CD160. Assessing the functional impact of HVEM binding to specific ligands in dif...

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Detalles Bibliográficos
Autores principales: Liu, Weifeng, Chou, Ting-Fang, Garrett-Thomson, Sarah C., Seo, Goo-Young, Fedorov, Elena, Ramagopal, Udupi A., Bonanno, Jeffrey B., Wang, Qingyang, Kim, Kenneth, Garforth, Scott J., Kakugawa, Kiyokazu, Cheroutre, Hilde, Kronenberg, Mitchell, Almo, Steven C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558838/
https://www.ncbi.nlm.nih.gov/pubmed/34709351
http://dx.doi.org/10.1084/jem.20211112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558838/
https://www.ncbi.nlm.nih.gov/pubmed/34709351
http://dx.doi.org/10.1084/jem.20211112

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