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Tau Protein Binding Modes in Alzheimer’s Disease for Cationic Luminescent Ligands

[Image: see text] The bi-thiophene-vinylene-benzothiazole (bTVBT4) ligand developed for Alzheimer’s disease (AD)-specific detection of amyloid tau has been studied by a combination of several theoretical methods and experimental spectroscopies. With reference to the cryo-EM tau structure of the tau...

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Detalles Bibliográficos
Autores principales: Todarwal, Yogesh, Gustafsson, Camilla, Thi Minh, Nghia Nguyen, Ertzgaard, Ingrid, Klingstedt, Therése, Ghetti, Bernardino, Vidal, Ruben, König, Carolin, Lindgren, Mikael, Nilsson, K. Peter R., Linares, Mathieu, Norman, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8558859/
https://www.ncbi.nlm.nih.gov/pubmed/34643404
http://dx.doi.org/10.1021/acs.jpcb.1c06019