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L-carnitine ameliorates the muscle wasting of cancer cachexia through the AKT/FOXO3a/MaFbx axis

BACKGROUND: Recent studies suggest potential benefits of applying L-carnitine in the treatment of cancer cachexia, but the precise mechanisms underlying these benefits remain unknown. This study was conducted to determine the mechanism by which L-carnitine reduces cancer cachexia. METHODS: C2C12 cel...

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Detalles Bibliográficos
Autores principales: Wu, Changpeng, Zhu, Mingxing, Lu, Zongliang, Zhang, Yaowen, Li, Long, Li, Na, Yin, Liangyu, Wang, He, Song, Wei, Xu, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559414/
https://www.ncbi.nlm.nih.gov/pubmed/34724970
http://dx.doi.org/10.1186/s12986-021-00623-7