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Intra- and intertumoral heterogeneity of liver metastases in a patient with uveal melanoma revealed by single-cell RNA sequencing

Tumor heterogeneity is a major obstacle to the success of cancer treatment. An accurate understanding and recognition of tumor heterogeneity is critical in the clinical management of cancer patients. Here, we utilized single-cell RNA sequencing (scRNA-seq) to uncover the intra- and intertumoral hete...

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Detalles Bibliográficos
Autores principales: Lin, Weitao, Beasley, Aaron B., Ardakani, Nima Mesbah, Denisenko, Elena, Calapre, Leslie, Jones, Matthew, Wood, Benjamin A., Warburton, Lydia, Forrest, Alistair R. R., Gray, Elin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559622/
https://www.ncbi.nlm.nih.gov/pubmed/34470851
http://dx.doi.org/10.1101/mcs.a006111