Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster

Mammalian Hox gene clusters contain a range of CTCF binding sites. In addition to their importance in organizing a TAD border, which isolates the most posterior genes from the rest of the cluster, the positions and orientations of these sites suggest that CTCF may be instrumental in the selection of...

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Detalles Bibliográficos
Autores principales: Amândio, Ana Rita, Beccari, Leonardo, Lopez-Delisle, Lucille, Mascrez, Bénédicte, Zakany, Jozsef, Gitto, Sandra, Duboule, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559674/
https://www.ncbi.nlm.nih.gov/pubmed/34711654
http://dx.doi.org/10.1101/gad.348934.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559674/
https://www.ncbi.nlm.nih.gov/pubmed/34711654
http://dx.doi.org/10.1101/gad.348934.121

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