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Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster
Mammalian Hox gene clusters contain a range of CTCF binding sites. In addition to their importance in organizing a TAD border, which isolates the most posterior genes from the rest of the cluster, the positions and orientations of these sites suggest that CTCF may be instrumental in the selection of...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559674/ https://www.ncbi.nlm.nih.gov/pubmed/34711654 http://dx.doi.org/10.1101/gad.348934.121 |