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ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes

Energy-storing white adipocytes maintain their identity by suppressing the energy-burning thermogenic gene program of brown and beige adipocytes. Here, we reveal that the protein–protein interaction between the transcriptional coregulator ZFP423 and brown fat determination factor EBF2 is essential f...

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Detalles Bibliográficos
Autores principales: Shao, Mengle, Zhang, Qianbin, Truong, Ashley, Shan, Bo, Vishvanath, Lavanya, Li, Lin, Seale, Patrick, Gupta, Rana K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559675/
https://www.ncbi.nlm.nih.gov/pubmed/34620682
http://dx.doi.org/10.1101/gad.348780.121