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ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes
Energy-storing white adipocytes maintain their identity by suppressing the energy-burning thermogenic gene program of brown and beige adipocytes. Here, we reveal that the protein–protein interaction between the transcriptional coregulator ZFP423 and brown fat determination factor EBF2 is essential f...
Autores principales: | Shao, Mengle, Zhang, Qianbin, Truong, Ashley, Shan, Bo, Vishvanath, Lavanya, Li, Lin, Seale, Patrick, Gupta, Rana K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559675/ https://www.ncbi.nlm.nih.gov/pubmed/34620682 http://dx.doi.org/10.1101/gad.348780.121 |
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