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Opening the window for endothelial-to-hematopoietic transition

Definitive long-term hematopoietic stem cells (LT-HSCs) arise during embryogenesis in a process termed endothelial-to-hematopoietic transition (EHT), in which specialized hemogenic endothelial cells (HECs) transform into hematopoietic cells. The transcription factor RUNX1 marks HECs and is essential...

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Detalles Bibliográficos
Autores principales: Samarakkody, Ann Sanoji, Cantor, Alan B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559677/
https://www.ncbi.nlm.nih.gov/pubmed/34725127
http://dx.doi.org/10.1101/gad.349056.121