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Dissecting CTCF site function in a tense HoxD locus

In this issue of Genes & Development, Amândio and colleagues (pp. 1490–1509) dissect the function of a cluster of several CTCF binding sites in the HoxD cluster by iterative deletions in mice. They found additive functions for some, and intriguingly found that some sites function as insulators,...

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Detalles Bibliográficos
Autor principal: Bruneau, Benoit G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559678/
https://www.ncbi.nlm.nih.gov/pubmed/34725128
http://dx.doi.org/10.1101/gad.349089.121