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Cellular abundance shapes function in piRNA-guided genome defense

Defense against genome invaders universally relies on RNA-guided immunity. Prokaryotic CRISPR-Cas and eukaryotic RNA interference pathways recognize targets by complementary base-pairing, which places the sequences of their guide RNAs at the center of self/nonself discrimination. Here, we explore th...

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Detalles Bibliográficos
Autores principales: Genzor, Pavol, Konstantinidou, Parthena, Stoyko, Daniel, Manzourolajdad, Amirhossein, Marlin Andrews, Celine, Elchert, Alexandra R., Stathopoulos, Constantinos, Haase, Astrid D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559710/
https://www.ncbi.nlm.nih.gov/pubmed/34667116
http://dx.doi.org/10.1101/gr.275478.121