RBFOX splicing factors contribute to a broad but selective recapitulation of peripheral tissue splicing patterns in the thymus

Thymic epithelial cells (TEC) control the selection of a T cell repertoire reactive to pathogens but tolerant of self. This process is known to involve the promiscuous expression of virtually the entire protein-coding gene repertoire, but the extent to which TEC recapitulate peripheral isoforms, and...

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Detalles Bibliográficos
Autores principales: Jansen, Kathrin, Shikama-Dorn, Noriko, Attar, Moustafa, Maio, Stefano, Lopopolo, Maria, Buck, David, Holländer, Georg A., Sansom, Stephen N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559713/
https://www.ncbi.nlm.nih.gov/pubmed/34649931
http://dx.doi.org/10.1101/gr.275245.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559713/
https://www.ncbi.nlm.nih.gov/pubmed/34649931
http://dx.doi.org/10.1101/gr.275245.121

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