DNA Vaccines Targeting Novel Cancer-Associated Antigens Frequently Expressed in Head and Neck Cancer Enhance the Efficacy of Checkpoint Inhibitor

HPV-independent head and neck squamous cell carcinoma (HNSCC) is a common cancer globally. The overall response rate to anti-PD1 checkpoint inhibitors (CPIs) in HNSCC is ~16%. One major factor influencing the effectiveness of CPI is the level of tumor infiltrating T cells (TILs). Converting TILlow t...

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Detalles Bibliográficos
Autores principales: Wang, Chuan, Zainal, Nur Syafinaz, Chai, San Jiun, Dickie, James, Gan, Chai Phei, Zulaziz, Natasha, Lye, Bryan Kit Weng, Sutavani, Ruhcha V., Ottensmeier, Christian H., King, Emma V., Abraham, Mannil Thomas, Ismail, Siti Mazlipah binti, Lau, Shin Hin, Kallarakkal, Thomas George, Mun, Kein Seong, Zain, Rosnah binti, Abdul Rahman, Zainal Ariff, Thomas, Gareth J., Cheong, Sok Ching, Savelyeva, Natalia, Lim, Kue Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559892/
https://www.ncbi.nlm.nih.gov/pubmed/34733290
http://dx.doi.org/10.3389/fimmu.2021.763086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559892/
https://www.ncbi.nlm.nih.gov/pubmed/34733290
http://dx.doi.org/10.3389/fimmu.2021.763086

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