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Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats

Dorsal striatal dopamine transmission engages the cortico-striato-thalamo-cortical (CSTC) circuit, which is implicated in many neuropsychiatric diseases, including obsessive-compulsive disorder (OCD). Yet it is unknown if dorsal striatal dopamine hyperactivity is the cause or consequence of changes...

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Detalles Bibliográficos
Autores principales: Casado-Sainz, Agata, Gudmundsen, Frederik, Baerentzen, Simone L., Lange, Denise, Ringsted, Annemette, Martinez-Tejada, Isabel, Medina, Siria, Lee, Hedok, Svarer, Claus, Keller, Sune H., Schain, Martin, Kjaerby, Celia, Fisher, Patrick M., Cumming, Paul, Palner, Mikael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559920/
https://www.ncbi.nlm.nih.gov/pubmed/34725486
http://dx.doi.org/10.1038/s41386-021-01207-y