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Dorsal striatal dopamine induces fronto-cortical hypoactivity and attenuates anxiety and compulsive behaviors in rats
Dorsal striatal dopamine transmission engages the cortico-striato-thalamo-cortical (CSTC) circuit, which is implicated in many neuropsychiatric diseases, including obsessive-compulsive disorder (OCD). Yet it is unknown if dorsal striatal dopamine hyperactivity is the cause or consequence of changes...
Autores principales: | Casado-Sainz, Agata, Gudmundsen, Frederik, Baerentzen, Simone L., Lange, Denise, Ringsted, Annemette, Martinez-Tejada, Isabel, Medina, Siria, Lee, Hedok, Svarer, Claus, Keller, Sune H., Schain, Martin, Kjaerby, Celia, Fisher, Patrick M., Cumming, Paul, Palner, Mikael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559920/ https://www.ncbi.nlm.nih.gov/pubmed/34725486 http://dx.doi.org/10.1038/s41386-021-01207-y |
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