Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR

Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with complex traits. However, a stringent significance threshold is required to identify robust genetic associations. Leveraging relevant auxiliary covariates has the potential to boost statistic...

Descripción completa

Detalles Bibliográficos
Autores principales: Hutchinson, Anna, Reales, Guillermo, Willis, Thomas, Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559959/
https://www.ncbi.nlm.nih.gov/pubmed/34669738
http://dx.doi.org/10.1371/journal.pgen.1009853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559959/
https://www.ncbi.nlm.nih.gov/pubmed/34669738
http://dx.doi.org/10.1371/journal.pgen.1009853

Ejemplares similares