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Leveraging auxiliary data from arbitrary distributions to boost GWAS discovery with Flexible cFDR
Genome-wide association studies (GWAS) have identified thousands of genetic variants that are associated with complex traits. However, a stringent significance threshold is required to identify robust genetic associations. Leveraging relevant auxiliary covariates has the potential to boost statistic...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559959/ https://www.ncbi.nlm.nih.gov/pubmed/34669738 http://dx.doi.org/10.1371/journal.pgen.1009853 |