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BRD4 promotes heterotopic ossification through upregulation of LncRNA MANCR

AIMS: Acquired heterotopic ossification (HO) is a debilitating disease characterized by abnormal extraskeletal bone formation within soft-tissues after injury. The exact pathogenesis of HO remains unknown. It was reported that BRD4 may contribute to osteoblastic differentiation. The current study ai...

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Detalles Bibliográficos
Autores principales: Liu, Lei, Li, ZiHao, Chen, Siwen, Cui, Haowen, Li, Xiang, Dai, Guo, Zhong, Fangling, Hao, Wenjun, Zhang, Kuibo, Liu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559974/
https://www.ncbi.nlm.nih.gov/pubmed/34657451
http://dx.doi.org/10.1302/2046-3758.1010.BJR-2020-0454.R1