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Reversing the surface charge of MSC‐derived small extracellular vesicles by εPL‐PEG‐DSPE for enhanced osteoarthritis treatment

Mesenchymal stem cell‐derived small extracellular vesicles (MSC‐sEVs) possess a great therapeutical potential for osteoarthritis (OA) treatment. However, the steric and electrostatic hindrance of cartilage matrix leads to very limited distribution of MSC‐sEVs in cartilage and low bioavailability of...

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Detalles Bibliográficos
Autores principales: Feng, Kai, Xie, Xuetao, Yuan, Ji, Gong, Liangzhi, Zhu, Zhaochen, Zhang, Juntao, Li, Haiyan, Yang, Yunlong, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559985/
https://www.ncbi.nlm.nih.gov/pubmed/34724347
http://dx.doi.org/10.1002/jev2.12160