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Reversing the surface charge of MSC‐derived small extracellular vesicles by εPL‐PEG‐DSPE for enhanced osteoarthritis treatment
Mesenchymal stem cell‐derived small extracellular vesicles (MSC‐sEVs) possess a great therapeutical potential for osteoarthritis (OA) treatment. However, the steric and electrostatic hindrance of cartilage matrix leads to very limited distribution of MSC‐sEVs in cartilage and low bioavailability of...
Autores principales: | Feng, Kai, Xie, Xuetao, Yuan, Ji, Gong, Liangzhi, Zhu, Zhaochen, Zhang, Juntao, Li, Haiyan, Yang, Yunlong, Wang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8559985/ https://www.ncbi.nlm.nih.gov/pubmed/34724347 http://dx.doi.org/10.1002/jev2.12160 |
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