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Multi-alleles predict primary non-response to infliximab therapy in Crohn’s disease
BACKGROUND: Infliximab (IFX) is the first-line treatment for patients with Crohn’s disease (CD) and is noted for its relatively high cost. The therapeutic efficacy of IFX has noticeable individual differences. Known single-gene polymorphisms (SNPs) are inadequate for predicting non-response to IFX....
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560039/ https://www.ncbi.nlm.nih.gov/pubmed/34733528 http://dx.doi.org/10.1093/gastro/goaa070 |