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Different B cell subpopulations show distinct patterns in their IgH repertoire metrics

Several human B cell subpopulations are recognised in the peripheral blood, which play distinct roles in the humoral immune response. These cells undergo developmental and maturational changes involving VDJ recombination, somatic hypermutation and class switch recombination, altogether shaping their...

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Detalles Bibliográficos
Autores principales: Ghraichy, Marie, von Niederhäusern, Valentin, Kovaltsuk, Aleksandr, Galson, Jacob D, Deane, Charlotte M, Trück, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560093/
https://www.ncbi.nlm.nih.gov/pubmed/34661527
http://dx.doi.org/10.7554/eLife.73111