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Increased Death of Peripheral Blood Mononuclear Cells after TLR4 Inhibition in Sepsis Is Not via TNF/TNF Receptor-Mediated Apoptotic Pathway

BACKGROUND: Apoptosis is one of the causes of immune depression in sepsis. Pyroptosis also occurs in sepsis. The toll-like receptor (TLR) 4 and receptor for advanced glycation end products (RAGE) have been shown to play important roles in apoptosis and pyroptosis. However, it is still unknown whethe...

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Detalles Bibliográficos
Autores principales: Chu, Chien-Ming, Chiu, Li-Chung, Yu, Chung-Chieh, Chuang, Li-Pang, Kao, Kuo-Chin, Li, Li-Fu, Wu, Huang-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560265/
https://www.ncbi.nlm.nih.gov/pubmed/34733114
http://dx.doi.org/10.1155/2021/2255017