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Arginase inhibition by rhaponticin increases L-arginine concentration that contributes to Ca(2+)-dependent eNOS activation

Although arginase primarily participates in the last reaction of the urea cycle, we have previously demonstrated that arginase II is an important cytosolic calcium regulator through spermine production in a p32-dependent manner. Here, we demonstrated that rhaponticin (RPT) is a novel medicinal-plant...

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Detalles Bibliográficos
Autores principales: Koo, Bon-Hyeock, Lee, Jonghoon, Jin, Younghyun, Lim, Hyun Kyo, Ryoo, Sungwoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560459/
https://www.ncbi.nlm.nih.gov/pubmed/34078530
http://dx.doi.org/10.5483/BMBRep.2021.54.10.053