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Entinostat, a histone deacetylase inhibitor, increases the population of IL-10(+) regulatory B cells to suppress contact hypersensitivity

IL-10(+) regulatory B (Breg) cells play a vital role in regulating the immune responses in experimental autoimmune encephalomyelitis, colitis, and contact hypersensitivity (CHS). Several sti-mulants such as lipopolysaccharide (LPS), CD40 ligand, and IL-21 spur the activation and maturation of IL-10(...

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Detalles Bibliográficos
Autores principales: Min, Keun Young, Lee, Min Bum, Hong, Seong Hwi, Lee, Dajeong, Jo, Min Geun, Lee, Ji Eon, Choi, Min Yeong, You, Jueng Soo, Kim, Young Mi, Park, Yeong Min, Kim, Hyuk Soon, Choi, Wahn Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560462/
https://www.ncbi.nlm.nih.gov/pubmed/34488930
http://dx.doi.org/10.5483/BMBRep.2021.54.10.092