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Entinostat, a histone deacetylase inhibitor, increases the population of IL-10(+) regulatory B cells to suppress contact hypersensitivity
IL-10(+) regulatory B (Breg) cells play a vital role in regulating the immune responses in experimental autoimmune encephalomyelitis, colitis, and contact hypersensitivity (CHS). Several sti-mulants such as lipopolysaccharide (LPS), CD40 ligand, and IL-21 spur the activation and maturation of IL-10(...
Autores principales: | Min, Keun Young, Lee, Min Bum, Hong, Seong Hwi, Lee, Dajeong, Jo, Min Geun, Lee, Ji Eon, Choi, Min Yeong, You, Jueng Soo, Kim, Young Mi, Park, Yeong Min, Kim, Hyuk Soon, Choi, Wahn Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560462/ https://www.ncbi.nlm.nih.gov/pubmed/34488930 http://dx.doi.org/10.5483/BMBRep.2021.54.10.092 |
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