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Implications of exosomes derived from cholesterol-accumulated astrocytes in Alzheimer's disease pathology

Amyloid β (Aβ) peptides generated from the amyloid precursor protein (APP) play a critical role in the development of Alzheimer's disease (AD) pathology. Aβ-containing neuronal exosomes, which represent a novel form of intercellular communication, have been shown to influence the function/vulne...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Cortez, Leonardo, Kamali-Jamil, Razieh, Sim, Valerie, Wille, Holger, Kar, Satyabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560497/
https://www.ncbi.nlm.nih.gov/pubmed/34524402
http://dx.doi.org/10.1242/dmm.048929