Intramolecular Disulfide Bonds for Biogenesis of CALHM1 Ion Channel Are Dispensable for Voltage-Dependent Activation

Calcium homeostasis modulator 1 (CALHM1) is a membrane protein with four transmembrane helices that form an octameric ion channel with voltage-dependent activation. There are four conserved cysteine (Cys) residues in the extracellular domain that form two intramolecular disulfide bonds. We investiga...

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Detalles Bibliográficos
Autores principales: Kwon, Jae Won, Jeon, Young Keul, Kim, Jinsung, Kim, Sang Jeong, Kim, Sung Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560582/
https://www.ncbi.nlm.nih.gov/pubmed/34711692
http://dx.doi.org/10.14348/molcells.2021.0131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560582/
https://www.ncbi.nlm.nih.gov/pubmed/34711692
http://dx.doi.org/10.14348/molcells.2021.0131

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