Cargando…

Intramolecular Disulfide Bonds for Biogenesis of CALHM1 Ion Channel Are Dispensable for Voltage-Dependent Activation

Calcium homeostasis modulator 1 (CALHM1) is a membrane protein with four transmembrane helices that form an octameric ion channel with voltage-dependent activation. There are four conserved cysteine (Cys) residues in the extracellular domain that form two intramolecular disulfide bonds. We investiga...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kwon, Jae Won, Jeon, Young Keul, Kim, Jinsung, Kim, Sang Jeong, Kim, Sung Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560582/ https://www.ncbi.nlm.nih.gov/pubmed/34711692 http://dx.doi.org/10.14348/molcells.2021.0131

Ejemplares similares

CALHM1/CALHM3 channel is intrinsically sorted to the basolateral membrane of epithelial cells including taste cells
por: Kashio, Makiko, et al.
Publicado: (2019)

CALHM1 ion channel mediates purinergic neurotransmission of sweet, bitter and umami tastes
por: Taruno, Akiyuki, et al.
Publicado: (2013)

Structure-activity relationships of the intramolecular disulfide bonds in coprisin, a defensin from the dung beetle
por: Lee, Jaeho, et al.
Publicado: (2014)

The ion channel CALHM6 controls bacterial infection‐induced cellular cross‐talk at the immunological synapse
por: Danielli, Sara, et al.
Publicado: (2023)

Cryo-EM structures and functional properties of CALHM channels of the human placenta
por: Drożdżyk, Katarzyna, et al.
Publicado: (2020)

A novel voltage-clamp/dye uptake assay reveals saturable transport of molecules through CALHM1 and connexin channels
por: Gaete, Pablo S., et al.
Publicado: (2020)

Gallocin A, an Atypical Two-Peptide Bacteriocin with Intramolecular Disulfide Bonds Required for Activity
por: Proutière, Alexis, et al.
Publicado: (2023)

Structure of human CALHM1 reveals key locations for channel regulation and blockade by ruthenium red
por: Syrjänen, Johanna L., et al.
Publicado: (2023)

Using Intramolecular Disulfide Bonds in Tau Protein to Deduce Structural Features of Aggregation-resistant Conformations
por: Walker, Sophie, et al.
Publicado: (2012)

Detection and function of an intramolecular disulfide bond in the pH-responsive CadC of Escherichia coli
por: Tetsch, Larissa, et al.
Publicado: (2011)

Disulfide mapping the voltage-sensing mechanism of a voltage-dependent potassium channel
por: Nozaki, Tomohiro, et al.
Publicado: (2016)

The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Na(v)1.7
por: Wright, Zoë V. F., et al.
Publicado: (2017)

The role of disulfide bond in hyperthermophilic endocellulase
por: Kim, Han-Woo, et al.
Publicado: (2013)

Microglial Calhm2 regulates neuroinflammation and contributes to Alzheimer’s disease pathology
por: Cheng, Jinbo, et al.
Publicado: (2021)

T-type, but not L-type, voltage-gated calcium channels are dispensable for lymphatic pacemaking and spontaneous contractions
por: To, Kim H. T., et al.
Publicado: (2020)

Effect of Calcium Ions and Disulfide Bonds on Swelling of Virus Particles
por: Asor, Roi, et al.
Publicado: (2019)

CALHM1 deficiency impairs cerebral neuron activity and memory flexibility in mice
por: Vingtdeux, Valérie, et al.
Publicado: (2016)

Intramolecular Hydrogen Bonding 2021
por: Jabłoński, Mirosław
Publicado: (2021)

Analysis of interaction between intracellular spermine and transient receptor potential canonical 4 channel: multiple candidate sites of negatively charged amino acids for the inward rectification of transient receptor potential canonical 4
por: Kim, Jinsung, et al.
Publicado: (2020)

Preventing Voltage-dependent Gating of Anthrax Toxin Channels Using Engineered Disulfides
por: Anderson, Damon S., et al.
Publicado: (2008)

Disulfide Bonds within the C2 Domain of RAGE Play Key Roles in Its Dimerization and Biogenesis
por: Wei, Wen, et al.
Publicado: (2012)

SOD1 gains pro-oxidant activity upon aberrant oligomerization: change in enzymatic activity by intramolecular disulfide bond cleavage
por: Yamazaki, Kosuke, et al.
Publicado: (2022)

A disulfide bond in the TIM23 complex is crucial for voltage gating and mitochondrial protein import
por: Ramesh, Ajay, et al.
Publicado: (2016)

Association of CALHM1 Gene Polymorphism with Late Onset Alzheimer's Disease in Iranian Population
por: Aqdam, Meysam Jafari, et al.
Publicado: (2010)

Two Highly Conserved Cysteine Residues in HPV16 L2 Form an Intramolecular Disulfide Bond and Are Critical for Infectivity in Human Keratinocytes
por: Campos, Samuel K., et al.
Publicado: (2009)

Voltage-Gated Lipid Ion Channels
por: Blicher, Andreas, et al.
Publicado: (2013)

Thermodynamics of voltage-gated ion channels
por: Zhang, Xuejun C., et al.
Publicado: (2018)

Palmitoylation of Voltage-Gated Ion Channels
por: Cassinelli, Silvia, et al.
Publicado: (2022)

Special Issue: Intramolecular Hydrogen Bonding
por: Castellano, Ronald K.
Publicado: (2014)

Introduction to “Intramolecular Hydrogen Bonding 2018”
por: Sánchez, Goar
Publicado: (2019)

Probing pattern and dynamics of disulfide bridges using synthesis and NMR of an ion channel blocker peptide toxin with multiple diselenide bonds
por: Fehér, Krisztina, et al.
Publicado: (2016)

CALHM1-Mediated ATP Release and Ciliary Beat Frequency Modulation in Nasal Epithelial Cells
por: Workman, Alan D., et al.
Publicado: (2017)

Voltage-Dependent Gating in a “Voltage Sensor-Less” Ion Channel
por: Kurata, Harley T., et al.
Publicado: (2010)

Coupled Movements in Voltage-gated Ion Channels
por: Horn, Richard
Publicado: (2002)

Regulating voltage-gated ion channels with nanobodies
por: Manning, Declan, et al.
Publicado: (2022)

Special Issue: Intramolecular Hydrogen Bonding 2017
por: Scheiner, Steve
Publicado: (2017)

Molecular Simulations of Disulfide-Rich Venom Peptides with Ion Channels and Membranes
por: Deplazes, Evelyne
Publicado: (2017)

Intramolecular cyclization of N-cyano sulfoximines by N–CN bond activation
por: Seo, Ye Ji, et al.
Publicado: (2023)

Multiple Disulfide-Bonded States of Native Proteins: Estimate of Number Using Probabilities of Disulfide Bond Formation
por: Hogg, Philip J.
Publicado: (2020)

Effect of intramolecular disulfide bond of bovine lactoferricin on its molecular structure and antibacterial activity against Trueperella pyogenes separated from cow milk with mastitis
por: Pei, Jie, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_212kgbsbpo98kokq0lo19t964b