D‐mannose alleviates osteoarthritis progression by inhibiting chondrocyte ferroptosis in a HIF‐2α‐dependent manner

OBJECTIVES: Chondrocyte ferroptosis contributes to osteoarthritis (OA) progression, and D‐mannose shows therapeutic value in many inflammatory conditions. Here, we investigated whether D‐mannose interferes in chondrocyte ferroptotic cell death during osteoarthritic cartilage degeneration. MATERIALS...

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Detalles Bibliográficos
Autores principales: Zhou, Xueman, Zheng, Yingcheng, Sun, Wentian, Zhang, Zhenzhen, Liu, Jiaqi, Yang, Wenke, Yuan, Wenxiu, Yi, Yating, Wang, Jun, Liu, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560605/
https://www.ncbi.nlm.nih.gov/pubmed/34561933
http://dx.doi.org/10.1111/cpr.13134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560605/
https://www.ncbi.nlm.nih.gov/pubmed/34561933
http://dx.doi.org/10.1111/cpr.13134

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