δ‐Tocotrienol sensitizes and re‐sensitizes ovarian cancer cells to cisplatin via induction of G1 phase cell cycle arrest and ROS/MAPK‐mediated apoptosis

OBJECTIVES: Among gynaecologic malignancies, ovarian cancer (OC) represents the leading cause of death for women worldwide. Current OC treatment involves cytoreductive surgery followed by platinum‐based chemotherapy, which is associated with severe side effects and development of drug resistance. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Fontana, Fabrizio, Marzagalli, Monica, Raimondi, Michela, Zuco, Valentina, Zaffaroni, Nadia, Limonta, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560608/
https://www.ncbi.nlm.nih.gov/pubmed/34520051
http://dx.doi.org/10.1111/cpr.13111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560608/
https://www.ncbi.nlm.nih.gov/pubmed/34520051
http://dx.doi.org/10.1111/cpr.13111

Ejemplares similares