Characterization and prognostic value of LXR splice variants in triple-negative breast cancer

Activity of liver x receptor (LXR), the homeostatic regulator of cholesterol metabolism, is elevated in triple-negative breast cancer (BCa) relative to other BCa subtypes, driving drug resistance and metastatic gene signatures. The loci encoding LXRα and LXRβ produce multiple alternatively spliced p...

Descripción completa

Detalles Bibliográficos
Autores principales: Lianto, Priscilia, Hutchinson, Samantha A., Moore, J. Bernadette, Hughes, Thomas A., Thorne, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560626/
https://www.ncbi.nlm.nih.gov/pubmed/34755086
http://dx.doi.org/10.1016/j.isci.2021.103212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560626/
https://www.ncbi.nlm.nih.gov/pubmed/34755086
http://dx.doi.org/10.1016/j.isci.2021.103212

Ejemplares similares