Cargando…

Characterization and prognostic value of LXR splice variants in triple-negative breast cancer

Activity of liver x receptor (LXR), the homeostatic regulator of cholesterol metabolism, is elevated in triple-negative breast cancer (BCa) relative to other BCa subtypes, driving drug resistance and metastatic gene signatures. The loci encoding LXRα and LXRβ produce multiple alternatively spliced p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lianto, Priscilia, Hutchinson, Samantha A., Moore, J. Bernadette, Hughes, Thomas A., Thorne, James L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560626/ https://www.ncbi.nlm.nih.gov/pubmed/34755086 http://dx.doi.org/10.1016/j.isci.2021.103212

Ejemplares similares

Phytosterols Inhibit Side-Chain Oxysterol Mediated Activation of LXR in Breast Cancer Cells
por: Hutchinson, Samantha A., et al.
Publicado: (2019)

ER-Negative Breast Cancer Is Highly Responsive to Cholesterol Metabolite Signalling
por: Hutchinson, Samantha A, et al.
Publicado: (2019)

Liver x receptor alpha drives chemoresistance in response to side-chain hydroxycholesterols in triple negative breast cancer
por: Hutchinson, Samantha A., et al.
Publicado: (2021)

Identification and characterization of alternative splicing variants of buffalo LXRα expressed in mammary gland
por: Fan, Xinyang, et al.
Publicado: (2022)

Signals from the various immune cells in promoting food allergy-induced eosinophilic esophagitis like disease
por: Lianto, Priscilia, et al.
Publicado: (2019)

LXR/RXR pathway signaling associated with triple-negative breast cancer in African American women
por: Torres-Luquis, Odalys, et al.
Publicado: (2018)

Expression of LXR-β, ABCA1 and ABCG1 in human triple-negative breast cancer tissues
por: Pan, Hailing, et al.
Publicado: (2019)

Inhibitory effects of quail egg on mast cells degranulation by suppressing PAR2-mediated MAPK and NF-kB activation
por: Lianto, Priscilia, et al.
Publicado: (2018)

Prognostic values of EDNRB in triple-negative breast cancer
por: Liu, Shaoqing, et al.
Publicado: (2020)

LXR-inverse agonism stimulates immune-mediated tumor destruction by enhancing CD8 T-cell activity in triple negative breast cancer
por: Carpenter, Katherine J., et al.
Publicado: (2019)

Encapsulation of LXR ligand by D-Nap-GFFY hydrogel enhances anti-tumorigenic actions of LXR and removes LXR-induced lipogenesis
por: Feng, Ke, et al.
Publicado: (2021)

LXRα and LXRβ Nuclear Receptors Evolved in the Common Ancestor of Gnathostomes
por: Fonseca, Elza, et al.
Publicado: (2017)

Prognostic and predictive value of Ki-67 in triple-negative breast cancer
por: Wang, Wei, et al.
Publicado: (2016)

Quail egg homogenate alleviates food allergy induced eosinophilic esophagitis like disease through modulating PAR-2 transduction pathway in peanut sensitized mice
por: Lianto, Priscilia, et al.
Publicado: (2018)

Novel Insights Into Triple-Negative Breast Cancer Prognosis by Comprehensive Characterization of Aberrant Alternative Splicing
por: Gong, Shasha, et al.
Publicado: (2020)

Transcriptional splice variants of CD40 and its prognostic value in breast cancer
por: ÜNVER, Neşe, et al.
Publicado: (2020)

LXR agonist inhibits inflammation through regulating MyD88 mRNA alternative splicing
por: Li, Ni, et al.
Publicado: (2022)

Verification and Validation of a Four-Gene Panel as a Prognostic Indicator in Triple Negative Breast Cancer
por: Pariyar, Mamta, et al.
Publicado: (2022)

Prognostic value of ERBB4 expression in patients with triple negative breast cancer
por: Kim, Ji-Yeon, et al.
Publicado: (2016)

Prognostic Value of Cancer Stem Cells Markers in Triple-Negative Breast Cancer
por: Collina, Francesca, et al.
Publicado: (2015)

Evaluation of the prognostic value of tumor-infiltrating lymphocytes in triple-negative breast cancers
por: Tian, Tian, et al.
Publicado: (2016)

Prognostic value of IMP3 immunohistochemical expression in triple negative breast cancer
por: Sjekloča, Nikoleta, et al.
Publicado: (2020)

WEE1 Dependency and Pejorative Prognostic Value in Triple‐Negative Breast Cancer
por: de Nonneville, Alexandre, et al.
Publicado: (2021)

Immune Lymphocyte Infiltrate and its Prognostic Value in Triple-Negative Breast Cancer
por: Huertas-Caro, Carlos Alexander, et al.
Publicado: (2022)

Prognostic value of various immune cells and Immunoscore in triple-negative breast cancer
por: Ren, Xinyu, et al.
Publicado: (2023)

Identfication of Potent LXRβ-Selective Agonists without LXRα Activation by In Silico Approaches
por: Chen, Meimei, et al.
Publicado: (2018)

Superenhancer drives a tumor-specific splicing variant of MARCO to promote triple-negative breast cancer progression
por: Yang, Yun-Song, et al.
Publicado: (2022)

Distinctive Prognostic Value and Cellular Functions of Osteopontin Splice Variants in Human Gastric Cancer
por: Hao, Chengcheng, et al.
Publicado: (2021)

The prognostic value of BRCA1 promoter methylation in early stage triple negative breast cancer
por: Sharma, Priyanka, et al.
Publicado: (2014)

miR-206 controls LXRα expression and promotes LXR-mediated cholesterol efflux in macrophages
por: Vinod, Manjula, et al.
Publicado: (2014)

Prognostic value of androgen receptor in triple negative breast cancer: A meta-analysis
por: Wang, Changjun, et al.
Publicado: (2016)

Prognostic value and immune landscapes of TERT promoter methylation in triple negative breast cancer
por: Lin, Fei, et al.
Publicado: (2023)

MYBL2 alternative splicing-related genetic variants reduce the risk of triple-negative breast cancer in the Chinese population
por: Chen, Xinyu, et al.
Publicado: (2023)

Establishment of a monoclonal antibody for human LXRα: Detection of LXRα protein expression in human macrophages
por: Watanabe, Yuichiro, et al.
Publicado: (2003)

Characterization of Redox-Responsive LXR-Activating Nanoparticle Formulations in Primary Mouse Macrophages
por: Smith, Tyler K. T., et al.
Publicado: (2019)

Prognostic Value of Osteopontin Splice Variant-c Expression in Breast Cancers: A Meta-Analysis
por: Hao, Chengcheng, et al.
Publicado: (2016)

The Prognostic Value of Nodal Staging in Triple-Negative Breast Cancer — A Cohort from China
por: Yin, Liu, et al.
Publicado: (2018)

Integrated analysis reveals prognostic value of HLA-I LOH in triple-negative breast cancer
por: Zhou, Yi-Fan, et al.
Publicado: (2021)

Prognostic value of tumor-infiltrating B lymphocytes and plasma cells in triple-negative breast cancer
por: Kuroda, Hajime, et al.
Publicado: (2021)

Prognostic and predictive value of circulating tumor DNA during neoadjuvant chemotherapy for triple negative breast cancer
por: Cavallone, Luca, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_02uvsmcp23hu3i8flnvbsppu6b