Easy or Not—The Advances of EZH2 in Regulating T Cell Development, Differentiation, and Activation in Antitumor Immunity

Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of polycomb repressive complex 2 (PRC2), which regulates downstream gene expression by trimethylation of lysine 27 in histone H3 (H3K27me3). EZH2 mutations or overexpressions are associated with many types of cancer. As inhibition of EZH2 a...

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Detalles Bibliográficos
Autores principales: Huang, Jiaqi, Zhang, Jie, Guo, Zhengyang, Li, Chen, Tan, Zhen, Wang, Junjie, Yang, Jianling, Xue, Lixiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560704/
https://www.ncbi.nlm.nih.gov/pubmed/34737746
http://dx.doi.org/10.3389/fimmu.2021.741302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560704/
https://www.ncbi.nlm.nih.gov/pubmed/34737746
http://dx.doi.org/10.3389/fimmu.2021.741302

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