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Calycosin Alleviates Sepsis-Induced Acute Lung Injury via the Inhibition of Mitochondrial ROS-Mediated Inflammasome Activation

Sepsis-induced acute lung injury (ALI) culminates in multiple organ failure via uncontrolled inflammatory responses and requires effective treatment. Herein, we aimed to investigate the effect of calycosin (CA), a natural isoflavonoid, on sepsis-induced ALI. CA attenuated lipopolysaccharide (LPS) an...

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Detalles Bibliográficos
Autores principales: Xia, Yu, Cao, Yuanbao, Sun, Yao, Hong, Xiuying, Tang, Yingyan, Yu, Juan, Hu, Hongjuan, Ma, Wenjia, Qin, Kailun, Bao, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560711/
https://www.ncbi.nlm.nih.gov/pubmed/34737695
http://dx.doi.org/10.3389/fphar.2021.690549