Microfluidic transfection of mRNA into human primary lymphocytes and hematopoietic stem and progenitor cells using ultra-fast physical deformations

Messenger RNA (mRNA) delivery provides gene therapy with the potential to achieve transient therapeutic efficacy without risk of insertional mutagenesis. Amongst other applications, mRNA can be employed as a platform to deliver gene editing molecules, to achieve protein expression as an alternative...

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Detalles Bibliográficos
Autores principales: Loo, Jocelyn, Sicher, Ian, Goff, Ailin, Kim, Ockchul, Clary, Nicole, Alexeev, Alexander, Sulchek, Todd, Zamarayeva, Alla, Han, Sewoon, Calero-Garcia, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560772/
https://www.ncbi.nlm.nih.gov/pubmed/34725429
http://dx.doi.org/10.1038/s41598-021-00893-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560772/
https://www.ncbi.nlm.nih.gov/pubmed/34725429
http://dx.doi.org/10.1038/s41598-021-00893-4

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