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The urinary excretion of epigenetically modified DNA as a marker of pediatric ALL status and chemotherapy response

The active DNA demethylation process may be linked to aberrant methylation and may be involved in leukemogenesis. We investigated the role of epigenetic DNA modifications in childhood acute lymphoblastic leukemia (ALL) diagnostics and therapy monitoring. We analyzed the levels of 5-methyl-2′-deoxycy...

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Detalles Bibliográficos
Autores principales: Rozalski, Rafal, Gackowski, Daniel, Skalska-Bugala, Aleksandra, Starczak, Marta, Siomek-Gorecka, Agnieszka, Zarakowska, Ewelina, Modrzejewska, Martyna, Dziaman, Tomasz, Szpila, Anna, Linowiecka, Kinga, Guz, Jolanta, Szpotan, Justyna, Gawronski, Maciej, Labejszo, Anna, Gackowska, Lidia, Foksinski, Marek, Olinska, Elwira, Wasilow, Aleksandra, Koltan, Andrzej, Styczynski, Jan, Olinski, Ryszard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560782/
https://www.ncbi.nlm.nih.gov/pubmed/34725426
http://dx.doi.org/10.1038/s41598-021-00880-9