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Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice

Aging is associated with significant changes in hematopoiesis that include a shift from lymphopoiesis to myelopoiesis and an expansion of phenotypic hematopoietic stem cells (HSCs) with impaired self-renewal capacity and myeloid-skewed lineage differentiation. Signals from commensal flora support ba...

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Detalles Bibliográficos
Autores principales: Krambs, Joseph R., Monlish, Darlene A., Gao, Feng, Schuettpelz, Laura G., Link, Daniel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560790/
https://www.ncbi.nlm.nih.gov/pubmed/34737755
http://dx.doi.org/10.3389/fimmu.2021.767267