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Microbiota Signals Suppress B Lymphopoiesis With Aging in Mice
Aging is associated with significant changes in hematopoiesis that include a shift from lymphopoiesis to myelopoiesis and an expansion of phenotypic hematopoietic stem cells (HSCs) with impaired self-renewal capacity and myeloid-skewed lineage differentiation. Signals from commensal flora support ba...
Autores principales: | Krambs, Joseph R., Monlish, Darlene A., Gao, Feng, Schuettpelz, Laura G., Link, Daniel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8560790/ https://www.ncbi.nlm.nih.gov/pubmed/34737755 http://dx.doi.org/10.3389/fimmu.2021.767267 |
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